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Memory in paediatric temporal lobe epilepsy: effects of lesion type and side.

Cormack, F; Vargha-Khadem, F; Wood, SJ; Cross, JH; Baldeweg, T; (2012) Memory in paediatric temporal lobe epilepsy: effects of lesion type and side. Epilepsy Research , 98 (2-3) 255 - 259. 10.1016/j.eplepsyres.2011.09.004. Green open access

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Abstract

This study investigated the role of underlying pathology on memory function of children with temporal lobe epilepsy (TLE). Memory was assessed in 44 children with TLE resulting from hippocampal sclerosis (HS) or dysembryoplastic neuroepithelial tumours (DNT), and 22 control children. Delayed story and paired associate recall performance was significantly more impaired in children with HS compared to those with DNT, irrespective of the affected side. Semantic memory was impaired in both HS groups, and also in the left DNT group. These results suggest a role for type, and to a lesser extent, side of pathology in the memory profile of children with TLE.

Type: Article
Title: Memory in paediatric temporal lobe epilepsy: effects of lesion type and side.
Location: Netherlands
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.eplepsyres.2011.09.004
Publisher version: http://dx.doi.org/10.1016/j.eplepsyres.2011.09.004
Language: English
Additional information: This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Keywords: Adolescent, Association Learning, Brain Neoplasms, Child, Epilepsy, Temporal Lobe, Female, Hippocampus, Humans, Magnetic Resonance Imaging, Male, Memory Disorders, Mental Recall, Neuropsychological Tests, Sclerosis, Teratoma, Verbal Learning
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health > Developmental Neurosciences Dept
URI: https://discovery.ucl.ac.uk/id/eprint/1329396
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