Romeo, DMM; Cioni, M; Scoto, M; Pizzardi, A; Romeo, MG; Guzzetta, A; (2009) Prognostic value of a scorable neurological examination from 3 to 12 months post-term age in very preterm infants: A longitudinal study. EARLY HUM DEV , 85 (6) 405 - 408. 10.1016/j.earlhumdev.2009.01.004.
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Aims and study design: The Hammersmith Infant Neurological Examination proved effective in predicting locomotor function in very preterm infants after 9 months of age. We performed the examination in a cohort of 103 very preterm infants (gestational age below 32 weeks) as early as 3 months' post-term age, and longitudinally at 6, 9 and 12 months. Our aim was to establish the frequency distribution of the optimality scores at each age period, to explore the predictive value of the examination from 3 months onwards as to developmental outcome and locomotor function at 2 years, and to explore its longitudinal consistency.Results: The results showed that this standardized neurological examination can be performed in preterm infants as early as 3 months' post-term age to predict motor outcome at 2 years. and that its high predictive value is consistent across the first year of life due to an effective combination of different items for each age period.Conclusions: We confirm the high predictive value of this neurological examination in very preterm infants after 9 months and extend it to the assessments performed as early as 3 months post-term. This is of great relevance as in very preterm infants early prediction of motor function is essential for a prompt planning of therapeutic interventions. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
|Title:||Prognostic value of a scorable neurological examination from 3 to 12 months post-term age in very preterm infants: A longitudinal study|
|Keywords:||Hammersmith Infant Neurological Examination, Prediction, Premature, Motor outcome, OPTIMALITY SCORE|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Child Health > Department of Neurosciences and Mental Health > ICH - Dubowitz Neuromuscular Centre|
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