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Maternal nodal and zebrafish embryogenesis.

Bennett, JT; Stickney, HL; Choi, W-Y; Ciruna, B; Talbot, WS; Schier, AF; (2007) Maternal nodal and zebrafish embryogenesis. Nature , 450 (7167) E1-E2. 10.1038/nature06314.

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Abstract

In fish and amphibians, the dorsal axis is specified by the asymmetric localization of maternally provided components of the Wnt signalling pathway. Gore et al. suggest that the Nodal signal Squint (Sqt) is required as a maternally provided dorsal determinant in zebrafish. Here we test their proposal and show that the maternal activities of sqt and the related Nodal gene cyclops (cyc) are not required for dorsoventral patterning.

Type: Article
Title: Maternal nodal and zebrafish embryogenesis.
Location: England
DOI: 10.1038/nature06314
Keywords: Animals, Body Patterning, Embryo, Nonmammalian, Female, Intracellular Signaling Peptides and Proteins, Models, Biological, Mothers, Nodal Signaling Ligands, Ovary, Ovum, RNA Splicing, Reproducibility of Results, Zebrafish, Zebrafish Proteins
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology
URI: http://discovery.ucl.ac.uk/id/eprint/1327551
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