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[Role of serotonin in the diffuse inhibitory controls induced by nociceptive stimulation].

Le Bars, D; Rivot, JP; Dickenson, AH; Chaouch, A; Besson, JM; (1980) [Role of serotonin in the diffuse inhibitory controls induced by nociceptive stimulation]. C R Seances Acad Sci D , 290 (4) pp. 379-382.

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Abstract

In the anaesthetized Rat, the entire population of dorsal horn convergent neurones is differentially affected by a noxious stimulus: while exciting the segmental pool, it strongly inhibits the remaining population. The inhibitory effects, which involve supraspinal mechanisms, are reduced to a great extent in parachlorophenylalanine pretreated animals. The role of raphé-spinal serotonergic pathways in nociception is discussed.

Type: Article
Title: [Role of serotonin in the diffuse inhibitory controls induced by nociceptive stimulation].
Location: France
Keywords: Animals, Fenclonine, Male, Neural Inhibition, Neural Pathways, Neurons, Pain, Rats, Serotonin, Spinal Nerve Roots
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Neuro, Physiology and Pharmacology
URI: http://discovery.ucl.ac.uk/id/eprint/132437
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