Kachramanoglou, C and Carlstedt, T and Koltzenburg, M and Choi, D (2011) Self-mutilation in patients after nerve injury may not be due to deafferentation pain: a case report. Pain Med , 12 (11) 1644 - 1648. 10.1111/j.1526-4637.2011.01242.x.
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Abstract
Animals with transected nerves may develop self-mutilating behavior (autotomy) directed at the denervated body part. Autotomy is often thought to be a response to deafferentation pain produced by pathological changes in the dorsal horn, and self-mutilation after dorsal rhizotomy has consequently been used as an outcome measure for the investigation of chronic pain in animal models. A less recognized hypothesis suggests that autotomy is simply an animal's efforts to remove the useless part. We report a case of self-mutilation of the thumb and fingers in a patient with loss of all sensory modalities in the arm after brachial plexus avulsion.
| Type: | Article |
|---|---|
| Title: | Self-mutilation in patients after nerve injury may not be due to deafferentation pain: a case report. |
| Location: | United States |
| DOI: | 10.1111/j.1526-4637.2011.01242.x |
| Language: | English |
| UCL classification: | UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology > Brain Repair and Rehabilitation UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Child Health > Department of Neurosciences and Mental Health > ICH - Neural Plasticity Unit |
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