Kachramanoglou, C; Carlstedt, T; Koltzenburg, M; Choi, D; (2011) Self-mutilation in patients after nerve injury may not be due to deafferentation pain: a case report. Pain Med , 12 (11) 1644 - 1648. 10.1111/j.1526-4637.2011.01242.x.
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Animals with transected nerves may develop self-mutilating behavior (autotomy) directed at the denervated body part. Autotomy is often thought to be a response to deafferentation pain produced by pathological changes in the dorsal horn, and self-mutilation after dorsal rhizotomy has consequently been used as an outcome measure for the investigation of chronic pain in animal models. A less recognized hypothesis suggests that autotomy is simply an animal's efforts to remove the useless part. We report a case of self-mutilation of the thumb and fingers in a patient with loss of all sensory modalities in the arm after brachial plexus avulsion.
|Title:||Self-mutilation in patients after nerve injury may not be due to deafferentation pain: a case report.|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology > Brain Repair and Rehabilitation|
UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology > Motor Neuroscience and Movement Disorders
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