Maréchal, A;
Meunier, B;
Lee, D;
Orengo, C;
Rich, PR;
(2012)
Yeast cytochrome c oxidase: a model system to study mitochondrial forms of the haem-copper oxidase superfamily.
Biochimica et Biophysica Acta (BBA) - Bioenergetics
, 1817
(4)
620 - 628.
10.1016/j.bbabio.2011.08.011.
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Abstract
The known subunits of yeast mitochondrial cytochrome c oxidase are reviewed. The structures of all eleven of its subunits are explored by building homology models based on the published structures of the homologous bovine subunits and similarities and differences are highlighted, particularly of the core functional subunit I. Yeast genetic techniques to enable introduction of mutations into the three core mitochondrially-encoded subunits are reviewed.
| Type: | Article |
|---|---|
| Title: | Yeast cytochrome c oxidase: a model system to study mitochondrial forms of the haem-copper oxidase superfamily. |
| Location: | Netherlands |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.bbabio.2011.08.011 |
| Publisher version: | http://dx.doi.org/10.1016/j.bbabio.2011.08.011 |
| Language: | English |
| Additional information: | This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| Keywords: | Animals, Cattle, Electron Transport Complex IV, Heme, Mitochondria, Models, Molecular, Mutation, Oxidoreductases, Protein Structure, Quaternary, Protein Subunits, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Structural and Molecular Biology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1323117 |
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