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Sesame oil use in ameliorating cough in children: A randomised controlled trial

Saab, BR; Pashayan, N; El-Chemaly, S; Sabra, R; (2006) Sesame oil use in ameliorating cough in children: A randomised controlled trial. COMPLEMENT THER MED , 14 (2) 92 - 99. 10.1016/j.ctim.2006.03.007.

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Abstract

Objectives: To examine the role of sesame oil (SO) in reducing the frequency and severity of acute cough in children 2-12 years of age.Design: Double blind, placebo controlled randomised trial.Setting: Seven primary health care centres/clinics in Lebanon. A total of 107 children between the age of 2 and 12 years with cough secondary to common cold were enrolled.Intervention: Five milliliters of SO or placebo by mouth at bed time.Outcome measures: Cough strength and frequency as judged by parents on a four points Likert scale after giving three syrup doses over three consecutive nights. Analysis was performed on an intention to treat basis. Results: At day 1, the effect size for cough frequency and cough strength were +0.26 (95%Cl -0.64,+0.12) and +0.15 (95%Cl -0.53, +0.23), respectively. SO decreased cough symptoms more than placebo but these were not statistically significant. The effect size decreased from days 1 to 3. Cough symptoms improved over the 3 days both in SO and placebo group. No evidence of undesirable effects were noted to SO.Conclusion: Like other over the counter anti-tussives, SO did not result in marked improvement in cough symptoms. (C) 2006 Elsevier Ltd. All rights reserved.

Type: Article
Title: Sesame oil use in ameliorating cough in children: A randomised controlled trial
DOI: 10.1016/j.ctim.2006.03.007
Keywords: sesame oil, cough, chidren, traditional medcine, SYMPTOMS, QUALITY, PLACEBO, ACID, RATS
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health > Applied Health Research
URI: http://discovery.ucl.ac.uk/id/eprint/1321860
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