Mustapa, MFM; Harris, R; Mould, J; Chubb, NAL; Schultz, D; Driscoll, PC; Tabor, AB; (2002) Synthesis of orthogonally protected lanthionines: a reassessment of the use of alanyl beta-cation equivalents. TETRAHEDRON LETT , 43 (46) 8359 - 8362.
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Whilst developing a strategy for the solid-phase synthesis of lanthionine-containing peptides, we became aware of sonic problems with a previously published route for the synthesis of orthogonally-protected lanthionine. We report a structural reassignment of the key iodoalanine intermediate and resulting lanthionine derivatives. (C) 2002 Elsevier Science Ltd. All rights reserved.
|Title:||Synthesis of orthogonally protected lanthionines: a reassessment of the use of alanyl beta-cation equivalents|
|Keywords:||CONFORMATIONAL PROPERTIES, DERIVATIVES, PEPTIDE, ANALOGS|
|UCL classification:||UCL > School of BEAMS > Faculty of Maths and Physical Sciences > Chemistry|
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