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Evolving Plastic Responses in Artificial Cell Models

Maher, J; Morgan, F; Mac Aodha, O; (2009) Evolving Plastic Responses in Artificial Cell Models. In: 2009 IEEE CONGRESS ON EVOLUTIONARY COMPUTATION, VOLS 1-5. (pp. 3018 - 3023). IEEE

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Abstract

Two variants of biologically inspired cell model, namely eukaryotic (containing a nucleus) and prokaryotic (without a nucleus) are compared in this research. The comparison investigates their relative evolvability and ability to integrate external environmental stimulus to direct protein pattern formation within a single cell. To the authors' knowledge there has been no reported work comparing the relative performance of eukaryotic and prokaryotic artificial cells models. We propose a novel system of protein translocation for eukaryotic cells based on the process of nucleocytoplasmic transport observed in biological cells. Results demonstrate that eukaryotic cell models exhibit a higher degree of sensitivity to environmental variations compared with prokaryotes. Based on these results we conclude that the process of transporting proteins to and from the nucleus plays a key role in shaping eukaryotic cell plasticity.

Type: Proceedings paper
Title: Evolving Plastic Responses in Artificial Cell Models
Event: IEEE Congress on Evolutionary Computation
Location: Trondheim, NORWAY
Dates: 2009-05-18 - 2009-05-21
ISBN-13: 978-1-4244-2958-5
Keywords: PHENOTYPIC PLASTICITY
UCL classification: UCL > School of BEAMS > Faculty of Engineering Science > Computer Science
URI: http://discovery.ucl.ac.uk/id/eprint/1317554
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