ISOLATED HLA-DP MISMATCHES BETWEEN DONORS AND RECIPIENTS DO NOT INFLUENCE THE FUNCTION OR OUTCOME OF RENAL-TRANSPLANTS.
5 - 9.
The matching of donors and renal graft recipients for human leukocyte antigens A, B, and DR has been shown to exert beneficial effects on the out-come of transplanation. Until the advent of polymerase chain reaction amplification-based genotyping, the effect of HLA-DP compatibility on graft survival could not be thoroughly investigated. HLA-DP compatibility has been determined in three living-related transplants and 34 cadaveric transplants for donor-recipient pairs matched for HLA-DR and -DQ. The effect of DP mismatching on graft surival and function was assessed. No clear benefit from matching donor and recipient for HLA-DP could be discerned.
|Title:||ISOLATED HLA-DP MISMATCHES BETWEEN DONORS AND RECIPIENTS DO NOT INFLUENCE THE FUNCTION OR OUTCOME OF RENAL-TRANSPLANTS|
|UCL classification:||UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences
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