ROSENBERG, WMC and BUSHELL, A and HIGGINS, RM and WORDSWORTH, BP and WOOD, KJ and BELL, JI and MORRIS, PJ (1992) ISOLATED HLA-DP MISMATCHES BETWEEN DONORS AND RECIPIENTS DO NOT INFLUENCE THE FUNCTION OR OUTCOME OF RENAL-TRANSPLANTS. HUM IMMUNOL , 33 (1) 5 - 9.
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The matching of donors and renal graft recipients for human leukocyte antigens A, B, and DR has been shown to exert beneficial effects on the out-come of transplanation. Until the advent of polymerase chain reaction amplification-based genotyping, the effect of HLA-DP compatibility on graft survival could not be thoroughly investigated. HLA-DP compatibility has been determined in three living-related transplants and 34 cadaveric transplants for donor-recipient pairs matched for HLA-DR and -DQ. The effect of DP mismatching on graft surival and function was assessed. No clear benefit from matching donor and recipient for HLA-DP could be discerned.
|Title:||ISOLATED HLA-DP MISMATCHES BETWEEN DONORS AND RECIPIENTS DO NOT INFLUENCE THE FUNCTION OR OUTCOME OF RENAL-TRANSPLANTS|
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