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Renal hepatitis C in the absence of detectable serum or hepatic virus

Fowell, AJ; Sheron, N; Rosenberg, WMC; (2008) Renal hepatitis C in the absence of detectable serum or hepatic virus. LIVER INT , 28 (6) 889 - 891. 10.1111/j.1478-3231.2008.01672.x.

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Abstract

We report an apparently unique case where hepatitis C virus (HCV) RNA was identified in renal tissue from a patient with membranoproliferative glomerulonephritis and treated chronic hepatitis C, despite the absence of detectable virus in the serum or liver (COBAS Amplicor qualitative assay, lower limit of detection 50 IU/ml). The implications of this finding are discussed, with particular reference to current concepts regarding 'occult' hepatitis C infection.

Type: Article
Title: Renal hepatitis C in the absence of detectable serum or hepatic virus
DOI: 10.1111/j.1478-3231.2008.01672.x
Keywords: glomerulonephritis, hepatitis C, polymerase chain reaction, BLOOD MONONUCLEAR-CELLS, B-VIRUS, INFECTION, CRYOGLOBULINEMIA, PERSISTENCE, RNA, DISEASES
UCL classification: UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)
URI: http://discovery.ucl.ac.uk/id/eprint/1315205
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