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Control of vascular tone by purines and pyrimidines

Burnstock, G; (2010) Control of vascular tone by purines and pyrimidines. BRIT J PHARMACOL , 161 (3) 527 - 529. 10.1111/j.1476-5381.2010.00937.x.

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In this Commentary, the roles of uridine adenosine tetraphosphate as an endothelium-derived contracting or relaxing factor described in the paper by Tolle et al. are considered and put into the wider context of the mechanisms of control of vascular tone by purinergic signalling via receptors located on both smooth muscle and endothelial cells.

Title:Control of vascular tone by purines and pyrimidines
Keywords:purinergic, sympathetic nerves, endothelial cells, cotransmission, ATP, UTP, adenosine, Up(4)A, NERVES
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Life Sciences > Biosciences (Division of)

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