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Vas deferens - A model used to establish sympathetic cotransmission

Burnstock, G; Verkhratsky, A; (2010) Vas deferens - A model used to establish sympathetic cotransmission. TRENDS PHARMACOL SCI , 31 (3) 131 - 139. 10.1016/j.tips.2009.12.002.

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Abstract

The vas deferens has been used as a model for many diverse studies of different aspects of autonomic neuro-transmission since its introduction including, in particular, sympathetic cotransmission involving release of ATP and neuropeptide Y together with noradrenaline and prejunctional and postjunctional neuromodulation. It has also been used to study sympathetic reinnervation following vasectomy and castration, as well as the deleterious effects of diabetes, hypertension and chronic alcohol.

Type:Article
Title:Vas deferens - A model used to establish sympathetic cotransmission
DOI:10.1016/j.tips.2009.12.002
Keywords:SMOOTH-MUSCLE-CELLS, ALPHA(2A/D)-ADRENOCEPTOR KNOCKOUT MICE, SPONTANEOUSLY HYPERTENSIVE-RATS, NITRIC-OXIDE SYNTHASE, GUINEA-PIG, CONTRACTILE RESPONSES, ALPHA,BETA-METHYLENE ATP, POSTNATAL-DEVELOPMENT, REGIONAL-VARIATION, NERVE-STIMULATION
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Life Sciences > Biosciences (Division of)

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