GIEBISCH, G and KLEINROBBENHAAR, G and KLEINROBBENHAAR, J and RATHEISER, K and UNWIN, R (1993) RENAL AND EXTRARENAL SITES OF ACTION OF DIURETICS. CARDIOVASC DRUG THER , 7 11 - 21.
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Abstract
This paper provides (a) a survey of the basic tubule transport mechanisms of sodium and potassium ions along the nephron, (b) a comparison of the overall renal effects of two diuretic agents (torasemide and furosemide), as assessed by renal clearance techniques, (c) an analysis of the tubule sites of action of torasemide evaluated by free-flow micropuncture and microperfusion techniques, and (d) a brief evaluation of some extrarenal transport effects of loop diuretics.
| Type: | Article |
|---|---|
| Title: | RENAL AND EXTRARENAL SITES OF ACTION OF DIURETICS |
| Keywords: | TORASEMIDE, FUROSEMIDE, RENAL CLEARANCE, MICROPUNCTURE, MICROPERFUSION, LOOP DIURETICS, THICK ASCENDING LIMB, CORTICAL COLLECTING TUBULE, POTASSIUM-TRANSPORT, DISTAL TUBULE, CELL-VOLUME, APICAL MEMBRANE, INHIBITS NACL, K-ATPASE, RAT, TORASEMIDE |
| UCL classification: | UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of) > Internal Medicine |
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