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Devolving of statin prescribing to general practitioners for HIV-infected patients receiving antiretroviral therapy

Benn, PD; Miller, RF; Evans, L; Minton, J; Edwards, SG; (2009) Devolving of statin prescribing to general practitioners for HIV-infected patients receiving antiretroviral therapy. International Journal of STD and AIDS , 20 (3) 202 - 204. 10.1258/ijsa.2008.008273.

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Abstract

Serious adverse events and medication errors are common in clinical practice and are associated with significant morbidity and mortality. Management of HIV-positive patients is likely to become more complex as people age, developing multiple medical conditions and thus requiring polypharmacy. We undertook a casenote review and interview of patients on antiretroviral therapy (ART) to audit the safety of devolving statin prescribing to general practitioners (GPs). Of 26 patients only 50% had their statin prescribing successfully been devolved to GPs. Many experienced significant difficulties and two of 26 (8%) were switched to simvastatin while receiving a protease inhibitor. We demonstrate that prescribing ART and non-ART medication by different practitioners on different sites can potentially expose patients to serious life-threatening adverse events. We make recommendations to minimize these risks and suggest that care pathways are reviewed to ensure they remain both convenient and user-friendly without compromising patient safety.

Type: Article
Title: Devolving of statin prescribing to general practitioners for HIV-infected patients receiving antiretroviral therapy
DOI: 10.1258/ijsa.2008.008273
Publisher version: http://doi.org/10.1258/ijsa.2008.008273
Language: English
Keywords: HIV, antiretroviral therapy, statins, drug–drug interactions, general practitioners
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute for Global Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute for Global Health > Infection and Population Health
URI: http://discovery.ucl.ac.uk/id/eprint/1307012
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