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Substantial variation in qPCR measured mean blood telomere lengths in young men from eleven European countries.

Eisenberg, DT; Salpea, KD; Kuzawa, CW; Hayes, MG; Humphries, SE; European Atherosclerosis Research Study II Group,; (2011) Substantial variation in qPCR measured mean blood telomere lengths in young men from eleven European countries. Am J Hum Biol , 23 (2) 228 - 231. 10.1002/ajhb.21126.

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Abstract

Telomeres, repetitive DNA sequences found at the ends of chromosomes, shorten with age in proliferating human tissues and are implicated in senescence. Previous studies suggest that shorter telomeres impair immune and cardiovascular function and result in increased mortality. Although few, prior studies have documented ethnic/population differences in human telomere lengths. The nature and cause(s) of these population differences remain poorly understood.

Type:Article
Title:Substantial variation in qPCR measured mean blood telomere lengths in young men from eleven European countries.
Location:United States
DOI:10.1002/ajhb.21126
Language:English
Keywords:Adolescent, Adult, Blood Cells, Case-Control Studies, Cohort Studies, Europe, European Continental Ancestry Group, Humans, Male, Myocardial Infarction, Polymerase Chain Reaction, Telomere, Young Adult
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science

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