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Comparison of Gal and non-Gal-mediated cardiac xenograft rejection.

Tazelaar, HD; Byrne, GW; McGregor, CG; (2011) Comparison of Gal and non-Gal-mediated cardiac xenograft rejection. Transplantation , 91 (9) 968 - 975. 10.1097/TP.0b013e318212c7fe.

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Abstract

This study compares the pathologic condition of delayed xenograft rejection in Gal-positive and Gal-knockout cardiac xenografts after pig-to-baboon heterotopic cardiac xenotransplantation when the induced anti-Gal antibody response is unregulated, blocked, or absent.

Type:Article
Title:Comparison of Gal and non-Gal-mediated cardiac xenograft rejection.
Location:United States
DOI:10.1097/TP.0b013e318212c7fe
Language:English
Keywords:Animals, Antibodies, Heterophile, Galactosyltransferases, Gene Knockout Techniques, Graft Rejection, Heart Transplantation, Microvessels, Myocytes, Cardiac, Necrosis, Papio, Swine, Thrombosis, Transplantation, Heterologous, Trisaccharides
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science

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