Walley, AJ and Jacobson, P and Falchi, M and Bottolo, L and Andersson, JC and Petretto, E and Bonnefond, A and Vaillant, E and Lecoeur, C and Vatin, V and Jernas, M and Balding, D and Petteni, M and Park, YS and Aitman, T and Richardson, S and Sjostrom, L and Carlsson, LM and Froguel, P (2012) Differential coexpression analysis of obesity-associated networks in human subcutaneous adipose tissue. Int J Obes (Lond) , 36 (1) 137 - 147. 10.1038/ijo.2011.22.
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Abstract
To use a unique obesity-discordant sib-pair study design to combine differential expression analysis, expression quantitative trait loci (eQTLs) mapping and a coexpression regulatory network approach in subcutaneous human adipose tissue to identify genes relevant to the obese state.
| Type: | Article |
|---|---|
| Title: | Differential coexpression analysis of obesity-associated networks in human subcutaneous adipose tissue. |
| Location: | England |
| DOI: | 10.1038/ijo.2011.22 |
| Language: | English |
| Additional information: | PMCID: PMC3160485 |
| Keywords: | Adolescent, Adult, Animals, Body Mass Index, Cell Adhesion Molecules, Cell Adhesion Molecules, Neuronal, Cohort Studies, Female, GPI-Linked Proteins, Gene Expression Regulation, Genetic Linkage, Genome-Wide Association Study, Humans, Male, Middle Aged, Obesity, Protein Array Analysis, Quantitative Trait Loci, Real-Time Polymerase Chain Reaction, Siblings, Subcutaneous Fat, Sweden, Thinness, Young Adult |
| UCL classification: | UCL > School of Life and Medical Sciences > Faculty of Life Sciences > Biosciences (Division of) > Genetics, Evolution and Environment > UCL Genetics Institute |
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