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OPINION The structural basis of inter-individual differences in human behaviour and cognition

Kanai, R and Rees, G (2011) OPINION The structural basis of inter-individual differences in human behaviour and cognition. NAT REV NEUROSCI , 12 (4) 231 - 242. 10.1038/nrn3000.

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Abstract

Inter-individual variability in perception, thought and action is frequently treated as a source of 'noise' in scientific investigations of the neural mechanisms that underlie these processes, and discarded by averaging data from a group of participants. However, recent MRI studies in the human brain show that inter-individual variability in a wide range of basic and higher cognitive functions - including perception, motor control, memory, aspects of consciousness and the ability to introspect - can be predicted from the local structure of grey and white matter as assessed by voxel-based morphometry or diffusion tensor imaging. We propose that inter-individual differences can be used as a source of information to link human behaviour and cognition to brain anatomy.

Type:Article
Title:OPINION The structural basis of inter-individual differences in human behaviour and cognition
DOI:10.1038/nrn3000
Keywords:VOXEL-BASED MORPHOMETRY, PREDICTS INDIVIDUAL-DIFFERENCES, WHITE-MATTER INTEGRITY, DOPAMINE-RECEPTOR AVAILABILITY, WORKING-MEMORY CAPACITY, REGIONAL BRAIN VOLUMES, HUMAN CEREBRAL-CORTEX, HUMAN VISUAL-CORTEX, CORTICAL THICKNESS, NEURAL BASIS
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Psychology and Language Sciences (Division of) > Institute of Cognitive Neuroscience
UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology > Imaging Neuroscience

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