Somasundaram, SK and Chicken, DW and Waddington, WA and Bomanji, J and Ell, PJ and Keshtgar, MRS (2009) Sentinel node imaging in breast cancer using superficial injections: Technical details and observations. EJSO-EUR J SURG ONC , 35 (12) 1250 - 1256. 10.1016/j.ejso.2009.05.006.
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Introduction: Sentinel lymph node (SLN) biopsy is the evolving standard of care for the management of early breast cancer. Accurate identification of the SLN is paramount for success of this procedure. Various techniques are described for SLN identification, but the superficial injection techniques, advocated by the UK National Training Programme (NEW START), are validated, reproducible and rapid. Pre-operative lymphoscintigraphy provides a road map for the surgeon and requires a reporting template.Methods: As one of the NEW START training institutions in the UK practising this technique, we reviewed a mature series of 100 unselected, consecutive SLN lymphoscintigraphy procedures. We correlated the imaging, operative and pathology findings and have provided technical details of the technique and a template for reporting SLN lymphoscintigrams.Results: The SLN localisation rate was 99% with one failed imaging. Seven patients required delayed imaging. The mean activity of the radiocolloid injected was 14.4 MBq (range 8.3-23 MBq). The SLNs were visualised in the ipsilateral axilla in 98 images, intramammary in 3, and internal mammary in 1. A mean of 1.35 nodes were classified as 'True' SLNs on imaging criteria. Intra-operatively, a mean of 1.91 SLNs were excised. 32 of 116 hot and blue nodes, 7 of 15 only blue nodes, 13 of 47 only hot and 7 of 13 parasentinel nodes harboured metastases.Conclusion: The NEW START recommended, combined superficial injection techniques, have high localisation rates. Pre-operative sentinel node imaging is recommended and a template for reporting is provided. (C) 2009 Elsevier Ltd. All rights reserved.
|Title:||Sentinel node imaging in breast cancer using superficial injections: Technical details and observations|
|Keywords:||Breast cancer, Sentinel lymph node biopsy, NEW START, Lymphoscintigraphy, Reporting template, LYMPH-NODE, BLUE-DYE, PREOPERATIVE LYMPHOSCINTIGRAPHY, SUBAREOLAR INJECTION, PATENT BLUE, BIOPSY, VALIDATION, DISSECTION, TRIAL, PROGRAM|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Surgery and Interventional Science (Division of)|
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