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Biomarkers in Peripheral Arterial Disease

Thomas, JC; Vohra, RS; Beer, S; Bhatti, K; Ponnambalam, S; Homer-Vanniasinkam, S; (2009) Biomarkers in Peripheral Arterial Disease. TRENDS CARDIOVAS MED , 19 (5) 147 - 151.

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Abstract

Patients who have peripheral arterial disease (PAD) have a high incidence of cardiac morbidity and mortality. There have been numerous biomarkers described to assess cardiovascular risk, but few are part of routine clinical practice. Currently, the key biomarkers that improve risk stratification in patients with PAD are cardiac troponins, C-reactive protein, and B-type natriuretic peptide. Recent advances in descriptive proteomics will offer future potential for biomarker discovery. However, it is essential that new markers are translated into tools for patient care. This review examines the potential biomarkers that improve cardiovascular risk stratification in PAD and avenues for future studies. (Trends Cardiovasc Med 2009;19:147-151) (C) 2009, Elsevier Inc.

Type:Article
Title:Biomarkers in Peripheral Arterial Disease
Keywords:C-REACTIVE PROTEIN, MAJOR VASCULAR-SURGERY, ACUTE CORONARY SYNDROME, MYOCARDIAL-INFARCTION, CARDIAC TROPONIN, NATRIURETIC PEPTIDE, STATIN THERAPY, CARDIOVASCULAR-DISEASE, INFLAMMATORY MARKERS, HEMOSTATIC FACTORS
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Surgery and Interventional Science (Division of)

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