Lee, CC; Fitzmaurice, RJ; Caddick, S; (2009) 3,5-Isoxazoles from alpha-bromo-pentafluorophenyl vinylsulfonates: Synthesis of sulfonates and sulfonamides. ORG BIOMOL CHEM , 7 (21) 4349 - 4351. 10.1039/b911098d.
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The regioselective 1,3-dipolar cycloaddition of alpha-bromo-pentafluorophenyl vinylsulfonate with nitrile oxides has been used to rapidly access a range of 3,5-isoxazoles which could be converted directly to their corresponding sulfonamides.
|Title:||3,5-Isoxazoles from alpha-bromo-pentafluorophenyl vinylsulfonates: Synthesis of sulfonates and sulfonamides|
|Keywords:||1,3-DIPOLAR CYCLOADDITION, NITRILE OXIDES, ISOXAZOLES, ANALOGS, DERIVATIVES, NUCLEOSIDE, INHIBITORS|
|UCL classification:||UCL > School of BEAMS > Faculty of Maths and Physical Sciences > Chemistry|
UCL > VP Enterprise
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