Aspirin particle formation by electric-field-assisted release of droplets.
CHEM ENG SCI
3091 - 3097.
An aspirin solution flowing through a needle at 0.36ml h(-1) (10(-10) m(3) s(-1)) was subjected to an electric field of 0.36kV mm(-1) to generate droplets. The aspirin droplet size distribution generated was measured and is shown to be trimodal with the most significant size, similar to 6 mu m. Deposited droplets and their aspirin crystal relics were also studied by electron microscopy. Immediately after deposition, the droplets were remarkably uniform in size and produced particulate crystals << 10 mu m and were considerably more regular in morphology when compared with those formed without using an electric field. (c) 2005 Elsevier Ltd. All rights reserved.
|Title:||Aspirin particle formation by electric-field-assisted release of droplets|
|Keywords:||electric-field, biomedicine, aspirin particulates, droplets, CONE-JET MODE, DRY POWDER INHALERS, ELECTROSTATIC ATOMIZATION, ELECTROHYDRODYNAMIC ATOMIZATION, DRUG-DELIVERY, AEROSOL, LIQUIDS, ELECTROSPRAY, INHALATION, DEPOSITION|
|UCL classification:||UCL > School of BEAMS > Faculty of Engineering Science > Mechanical Engineering|
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