Marson, CM and Rioja, AS and Brooke, G and Coombes, RC and Vigushin, DM (2002) Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase. BIOORG MED CHEM LETT , 12 (2) 255 - 259.
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Abstract
Cyclic acid anhydrides possessing a lipid chain have been shown to be a new class of non-peptidic inhibitors of geranylgeranyl protein-transferase type I (GGPTase-I). (C) 2002 Elsevier Science Ltd. All rights reserved.
| Type: | Article |
|---|---|
| Title: | Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase |
| Keywords: | I INHIBITOR, FARNESYLTRANSFERASE INHIBITORS, PROTEIN GERANYLGERANYLATION, RAS PRENYLATION, K-RAS, GROWTH, FARNESYLATION, CELLS, TRANSFORMATION, REQUIRES |
| UCL classification: | UCL > School of BEAMS > Faculty of Maths and Physical Sciences > Chemistry |
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