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Cytoplasmic dynein nomenclature

Pfister, KK; Fisher, EMC; Gibbons, IR; Hays, TS; Holzbaur, ELF; McIntosh, JR; Porter, ME; ... Vallee, RB; + view all (2005) Cytoplasmic dynein nomenclature. J CELL BIOL , 171 (3) 411 - 413. 10.1083/jcb.200508078.

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Abstract

A variety of names has been used in the literature for the subunits of cytoplasmic dynein complexes. Thus, there is a strong need for a more definitive consensus statement on nomenclature. This is especially important for mammalian cytoplasmic dyneins, many subunits of which are encoded by multiple genes. We propose names for the mammalian cytoplasmic dynein subunit genes and proteins that reflect the phylogenetic relationships of the genes and the published studies clarifying the functions of the polypeptides. This nomenclature recognizes the two distinct cytoplasmic dynein complexes and has the flexibility to accommodate the discovery of new subunits and isoforms.

Type: Article
Title: Cytoplasmic dynein nomenclature
DOI: 10.1083/jcb.200508078
Keywords: LIGHT-CHAIN, RAT-BRAIN, FAMILY, IDENTIFICATION, TRANSPORT, MOTILITY
UCL classification: UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology
UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology > Neurodegenerative Diseases
URI: http://discovery.ucl.ac.uk/id/eprint/126639
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