Caddick, S and Delisser, VM and Doyle, VE and Khan, S and Avent, AG and Vile, S (1999) Studies toward the synthesis of natural and unnatural dienediynes 1. Approaches to a functionalised bicyclic ring system. TETRAHEDRON , 55 (9) 2737 - 2754.
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Abstract
The synthesis of a functionalised bicyclic ring system related to the naturally occurring dienediynes, NCS and Kedarcidin Chromophores is presented. Key steps involve: conjugate addition of an enediyne to a functionalised enone and intramolecular boron mediated aldol reaction. (C) 1999 Elsevier Science Ltd. All rights reserved.
| Type: | Article |
|---|---|
| Title: | Studies toward the synthesis of natural and unnatural dienediynes 1. Approaches to a functionalised bicyclic ring system |
| Keywords: | aldol reactions, cyclisation, diynes, NEOCARZINOSTATIN CHROMOPHORE, KEDARCIDIN CHROMOPHORES, ENEDIYNE, ANALOGS, AGENTS, MADUROPEPTIN, METHODOLOGY, MECHANISM, STRATEGY, C-1027 |
| UCL classification: | UCL > VP Enterprise |
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