Tada, M; Smith, JC; (2001) T-targets: Clues to understanding the functions of T-box proteins. DEV GROWTH DIFFER , 43 (1) 1 - 11.
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Members of the T-box gene family have been identified in both vertebrates and invertebrates, where they play key roles in the regulation of embryonic development, and particularly in morphogenesis and the assignment of cell fate. T-box proteins act as transcription factors which regulate the expression of downstream effector genes. This review focuses on the identification of T-box target genes and the basis of T-box functional specificity.
|Title:||T-targets: Clues to understanding the functions of T-box proteins|
|Keywords:||Brachyury, cell fate, morphogenesis, target genes, T-box, CONVERGENT EXTENSION MOVEMENTS, ULNAR-MAMMARY SYNDROME, NODAL-RELATED SIGNALS, TRANSCRIPTION FACTOR, MESODERM FORMATION, XENOPUS EMBRYOS, ENDODERM FORMATION, PLANAR POLARITY, TISSUE POLARITY, BRACHYURY GENE|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Life Sciences > Biosciences (Division of) > Cell and Developmental Biology|
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