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Review article: Pathogenesis and treatment of chronic hepatic encephalopathy

Jalan, R; Seery, JP; TaylorRobinson, SD; (1996) Review article: Pathogenesis and treatment of chronic hepatic encephalopathy. ALIMENT PHARM THERAP , 10 (5) 681 - 697.

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Abstract

The various treatment strategies for hepatic encephalopathy are compared in the light of the available body of scientific work on the pathogenesis of the syndrome, Data on animal models of hepatic encephalopathy and in vitro studies on brain slices are discussed. Difficulties in extrapolating the results obtained to the human situation are highlighted, while results of human positron emission tomography and magnetic resonance spectroscopy studies are outlined on the background of the potential weaknesses of these non-invasive techniques.

Type: Article
Title: Review article: Pathogenesis and treatment of chronic hepatic encephalopathy
Keywords: PORTAL-SYSTEMIC ENCEPHALOPATHY, BLOOD-BRAIN-BARRIER, BENZODIAZEPINE RECEPTOR LIGANDS, MAGNETIC-RESONANCE SPECTROSCOPY, GAMMA-AMINOBUTYRIC ACID, BLIND CONTROLLED TRIAL, ACUTE LIVER-FAILURE, PLASMA AMINO-ACIDS, CIRRHOTIC-PATIENTS, PORTACAVAL ANASTOMOSIS
URI: http://discovery.ucl.ac.uk/id/eprint/122154
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