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On the separation of signals from neighboring cells in tetrode recordings

Sahani, M; Pezaris, JS; Andersen, RA; (1998) On the separation of signals from neighboring cells in tetrode recordings. In: Jordan, MI and Kearns, MJ and Solla, SA, (eds.) ADVANCES IN NEURAL INFORMATION PROCESSING SYSTEMS 10. (pp. 222 - 228). M I T PRESS

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Abstract

We discuss a solution to the problem of separating waveforms produced by multiple cells in an extracellular neural recording. We take an explicitly probabilistic approach, using latent-variable models of varying sophistication to describe the distribution of waveforms produced by a single cell. The models range from a single Gaussian distribution of waveforms for each cell to a mixture of hidden Markov models. We stress the overall statistical structure of the approach, allowing the details of the generative model chosen to depend on the specific neural preparation.

Type:Proceedings paper
Title:On the separation of signals from neighboring cells in tetrode recordings
Event:11th Annual Conference on Neural Information Processing Systems (NIPS)
Location:DENVER, CO
Dates:1997-12-01 - 1997-12-06
ISBN:0-262-10076-2
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Life Sciences > Gatsby Computational Neuroscience Unit

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