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Standing the test of time: long-term outcome of reconstruction of the exstrophy bladder

Woodhouse, CRJ; North, AC; Gearhart, JP; (2006) Standing the test of time: long-term outcome of reconstruction of the exstrophy bladder. WORLD J UROL , 24 (3) 244 - 249. 10.1007/s00345-006-0053-7.

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Abstract

The surgical management of classic bladder exstrophy has evolved over time. Different techniques are used to address the challenge of reconstructing these patients. We review the long-term outcomes of bladder exstrophy treatment from the published literature with regard to urinary continence, voiding and secondary complications. Continence now can be achieved in up to 80% of children in specialist centres. Whether such success can sustained into adult life is uncertain. About 40% of adults are dry in the best hands. Up to 84% of children can void, but there is some evidence that this function is lost with time in 70%. The need for bladder augmentation is widely variable between series, reported in 0-70% of children. This reduces the ability to void spontaneously to about 50% of children. It brings with it the later risk of metabolic disturbance and stone formation. Adults with exstrophy have a 694-fold increase in the risk of bladder cancer by the age of 40 years.

Type: Article
Title: Standing the test of time: long-term outcome of reconstruction of the exstrophy bladder
DOI: 10.1007/s00345-006-0053-7
Keywords: bladder exstrophy, urinary incontinence, follow-up, COMPLETE PRIMARY REPAIR, NECK RECONSTRUCTION, CONTINENCE, EPISPADIAS, EXPERIENCE, CHILDREN, CLOSURE, LIFE
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention
URI: http://discovery.ucl.ac.uk/id/eprint/120252
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