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An approach to the simulation of fluid-structure interaction in the aortic valve

Carmody, CJ; Burriesci, G; Howard, IC; Patterson, EA; (2006) An approach to the simulation of fluid-structure interaction in the aortic valve. J BIOMECH , 39 (1) 158 - 169. 10.1016/j.jbiomech.2004.10.038.

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A pair of finite element models has been employed to study the interaction of blood flow with the operation of the aortic valve. A three-dimensional model of the left ventricle with applied wall displacements has been used to generate data for the spatially and time-varying blood velocity profile across the aortic aperture. These data have been used as the inlet loading conditions in a three-dimensional model of the aortic valve and its surrounding structures. Both models involve fluid-structure interaction and simulate the cardiac cycle as a dynamic event. Confidence in the models was obtained by comparison with data obtained in a pulse duplicator. The results show a circulatory flow being generated in the ventricle which produces a substantially axial flow through the aortic aperture. The aortic valve behaves in an essentially symmetric way under the action of this flow, so that the pressure difference across the leaflets is approximately uniform. This work supports the use of spatially uniform but temporally variable pressure distributions across the leaflets in dry or structural models of aortic valves. The study is a major advance through its use of truly three-dimensional geometry, spatially non-uniform loading conditions for the valve leaflets and the successful modelling of progressive contact of the leaflets in a fluid environment. (c) 2004 Elsevier Ltd. All rights reserved.

Type: Article
Title: An approach to the simulation of fluid-structure interaction in the aortic valve
DOI: 10.1016/j.jbiomech.2004.10.038
Keywords: aortic valve, fluid-structure interaction, simulation, BIOPROSTHETIC HEART-VALVE, 3-DIMENSIONAL ANALYSIS, PROSTHESIS, MECHANICS, MOTION
UCL classification: UCL > School of BEAMS
UCL > School of BEAMS > Faculty of Engineering Science
URI: http://discovery.ucl.ac.uk/id/eprint/119087
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