Ratcliffe, PJ and Pugh, CW and Maxwell, PH (2000) Targeting tumors through the HIF system. NAT MED , 6 (12) 1315 - 1316.
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Hypoxia-inducible factor (HIF) is a key transcriptional regulator of the cellular response to hypoxia that is upregulated in many common cancers. Blockade of the pathway may provide a new opportunity for the development of cancer therapeutics.
|Title:||Targeting tumors through the HIF system|
|Keywords:||HYPOXIA, PROTEIN, ANGIOGENESIS, HIF-1-ALPHA, ENHANCER|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)|
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