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Targeting tumors through the HIF system

Ratcliffe, PJ; Pugh, CW; Maxwell, PH; (2000) Targeting tumors through the HIF system. NAT MED , 6 (12) 1315 - 1316.

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Abstract

Hypoxia-inducible factor (HIF) is a key transcriptional regulator of the cellular response to hypoxia that is upregulated in many common cancers. Blockade of the pathway may provide a new opportunity for the development of cancer therapeutics.

Type:Article
Title:Targeting tumors through the HIF system
Keywords:HYPOXIA, PROTEIN, ANGIOGENESIS, HIF-1-ALPHA, ENHANCER
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)

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