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The ketogenic diet - update on recent clinical trials

Cross, JH; Neal, EG; (2008) The ketogenic diet - update on recent clinical trials. EPILEPSIA , 49 6 - 10. 10.1111/j.1528-1167.2008.01822.x.

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Abstract

The ketogenic diet (KD) has been used in the treatment of epilepsy for almost 100 years. Several cohort studies have emphasized its possible benefit, although use became less at the introduction of anticonvulsant medication. However, the KD has regained recognition over the past 15 years. Resources remain scarce and its availability for children may be limited. One argument has been the lack of evidence from suitably designed trials. Systematic reviews and meta-analyses have revealed that studies are limited to class 3 and 4 data. A recently published randomized controlled trial has shown that the benefit of the KD is equivalent to any of the new anticonvulsant medications, emphasizing the need for more resources to ensure greater diet availability.

Type: Article
Title: The ketogenic diet - update on recent clinical trials
DOI: 10.1111/j.1528-1167.2008.01822.x
Keywords: Clinical trials, Ketogenic diet, Epilepsy, Childhood, INTRACTABLE CHILDHOOD EPILEPSY, CHAIN TRIGLYCERIDE DIET, REFRACTORY EPILEPSY, MULTICENTRIC EXPERIENCE, SEIZURE DISORDERS, EFFICACY, CHILDREN, THERAPY
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health > ICH Developmental Neurosciences Prog
URI: http://discovery.ucl.ac.uk/id/eprint/118289
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