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Nomenclature for the human Arf family of GTP-binding proteins: ARF, ARL, and SAR proteins

Kahn, RA; Cherfils, J; Elias, M; Lovering, RC; Munro, S; Schurmann, A; (2006) Nomenclature for the human Arf family of GTP-binding proteins: ARF, ARL, and SAR proteins. J CELL BIOL , 172 (5) 645 - 650. 10.1083/jcb.200512057.

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Abstract

The Ras superfamily is comprised of at least four large families of regulatory guanosine triphosphate-binding proteins, including the Arfs. The Arf family includes three different groups of proteins: the Arfs, Arf-like (Arls), and SARs. Several Arf family members have been very highly conserved throughout eukaryotic evolution and have orthologues in evolutionally diverse species. The different means by which Arf family members have been identified have resulted in an inconsistent and confusing array of names. This confusion is further compounded by differences in nomenclature between different species. We propose a more consistent nomenclature for the human members of the Arf family that may also serve as a guide for nomenclature in other species.

Type:Article
Title:Nomenclature for the human Arf family of GTP-binding proteins: ARF, ARL, and SAR proteins
DOI:10.1083/jcb.200512057
Keywords:ADP-RIBOSYLATION FACTOR, CHOLERA-TOXIN, FACTOR DOMAIN, ENDOPLASMIC-RETICULUM, REGULATORY COMPONENT, ADENYLATE-CYCLASE, GENOMIC ANALYSIS, COPII VESICLE, NUCLEOTIDE, CLONING
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science

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