Minihane, AM and Finnegan, YE and Talmud, P and Leigh-Firbank, EC and Williams, CM (2002) Influence of the APOC3-2854T > G polymorphism on plasma lipid levels: effect of age and gender. BBA-MOL CELL BIOL L , 1583 (3) 311 - 314.
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Abstract
The APOC3 - 2854T>G polymorphism lies in the APOO-A4 intergenic region. In a group of healthy adults, this polymorphism was associated with circulating triglycerides, with 55% lower fasting levels in the homozygous wild-type (TT) compared to the homozygous rare allele (GG) genotype. Age and gender had a significant impact on genotype - triglyceride interactions. (C) 2002 Elsevier Science B.V All rights reserved.
| Type: | Article |
|---|---|
| Title: | Influence of the APOC3-2854T > G polymorphism on plasma lipid levels: effect of age and gender |
| Keywords: | APOC3 polymorphism, -2854T > G, triglyceride, age, gender, blood lipid, APOLIPOPROTEIN-C-III, DENSITY-LIPOPROTEIN-CHOLESTEROL, TRANSGENIC MICE, GENE-CLUSTER, CIII GENE, A-I, HYPERTRIGLYCERIDEMIA, METABOLISM, TOLERANCE, DISEASE |
| UCL classification: | UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science |
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