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Influence of the APOC3-2854T > G polymorphism on plasma lipid levels: effect of age and gender

Minihane, AM; Finnegan, YE; Talmud, P; Leigh-Firbank, EC; Williams, CM; (2002) Influence of the APOC3-2854T > G polymorphism on plasma lipid levels: effect of age and gender. BBA-MOL CELL BIOL L , 1583 (3) 311 - 314.

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Abstract

The APOC3 - 2854T>G polymorphism lies in the APOO-A4 intergenic region. In a group of healthy adults, this polymorphism was associated with circulating triglycerides, with 55% lower fasting levels in the homozygous wild-type (TT) compared to the homozygous rare allele (GG) genotype. Age and gender had a significant impact on genotype - triglyceride interactions. (C) 2002 Elsevier Science B.V All rights reserved.

Type:Article
Title:Influence of the APOC3-2854T > G polymorphism on plasma lipid levels: effect of age and gender
Keywords:APOC3 polymorphism, -2854T > G, triglyceride, age, gender, blood lipid, APOLIPOPROTEIN-C-III, DENSITY-LIPOPROTEIN-CHOLESTEROL, TRANSGENIC MICE, GENE-CLUSTER, CIII GENE, A-I, HYPERTRIGLYCERIDEMIA, METABOLISM, TOLERANCE, DISEASE
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science

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