Stephens, JW and Hurel, SJ and Acharya, J and Humphries, SE (2004) An interaction between the interleukin-6 -174G>C gene variant and urinary protein excretion influences plasma oxidative stress in subjects with type 2 diabetes. Cardiovasc Diabetol , 3 2 - ?. 10.1186/1475-2840-3-2.
Abstract
Microalbuminuria and subsequent progression to proteinuria and nephropathy is associated with increased oxidative stress, increased inflammatory cytokines and increased cardiovascular (CVD) risk. The common functional IL-6 -174G>C gene variant is also associated with elevated levels of inflammatory cytokines and CVD risk.
| Type: | Article |
|---|---|
| Title: | An interaction between the interleukin-6 -174G>C gene variant and urinary protein excretion influences plasma oxidative stress in subjects with type 2 diabetes. |
| Location: | England |
| Open access status: | An open access publication |
| DOI: | 10.1186/1475-2840-3-2 |
| Language: | English |
| Additional information: | PMCID: PMC375540 |
| UCL classification: | UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science |
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