UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

An interaction between the interleukin-6 -174G>C gene variant and urinary protein excretion influences plasma oxidative stress in subjects with type 2 diabetes.

Stephens, JW; Hurel, SJ; Acharya, J; Humphries, SE; (2004) An interaction between the interleukin-6 -174G>C gene variant and urinary protein excretion influences plasma oxidative stress in subjects with type 2 diabetes. Cardiovasc Diabetol , 3 2 - ?. 10.1186/1475-2840-3-2. Gold open access

Abstract

Microalbuminuria and subsequent progression to proteinuria and nephropathy is associated with increased oxidative stress, increased inflammatory cytokines and increased cardiovascular (CVD) risk. The common functional IL-6 -174G>C gene variant is also associated with elevated levels of inflammatory cytokines and CVD risk.

Type:Article
Title:An interaction between the interleukin-6 -174G>C gene variant and urinary protein excretion influences plasma oxidative stress in subjects with type 2 diabetes.
Location:England
Open access status:An open access publication
DOI:10.1186/1475-2840-3-2
Language:English
Additional information:PMCID: PMC375540
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science

Archive Staff Only: edit this record