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Three novel mutations in the apolipoprotein E gene in a sample of individuals with type 2 diabetes mellitus.

Stephens, JW; Sozen, MM; Whittall, RA; Caslake, MJ; Bedford, D; Acharya, J; ... Humphries, SE; + view all (2005) Three novel mutations in the apolipoprotein E gene in a sample of individuals with type 2 diabetes mellitus. Clin Chem , 51 (1) 119 - 124. 10.1373/clinchem.2004.040121.

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Abstract

Apolipoprotein E (apoE) is found in association with triglyceride-rich lipoproteins and is the ligand for the removal of these particles from the plasma. Genetic variations in exon 4 lead to three common gene variants: E2, E3, and E4.

Type:Article
Title:Three novel mutations in the apolipoprotein E gene in a sample of individuals with type 2 diabetes mellitus.
Location:United States
DOI:10.1373/clinchem.2004.040121
Language:English
Keywords:Apolipoproteins E, Diabetes Mellitus, Type 2, Genotype, Humans, Isoelectric Focusing, Mutation, Phenotype, Sequence Analysis, DNA
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science

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