Hothi, DK; Bass, P; Morgan, M; Acharya, J; Humphries, SE; Gilbert, RD; (2007) Acute renal failure in a patient with paroxysmal cold hemoglobinuria. PEDIATR NEPHROL , 22 (4) 593 - 596. 10.1007/s00467-006-0352-7.
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Acute renal failure following auto-immune hemolysis is rare. We report a child with acute paroxysmal cold hemoglobinuria (PCH) complicated by renal failure. She was treated by peritoneal dialysis and red blood cell transfusion. After 2 weeks she had made a complete recovery with a normal blood count and renal profile, and the peritoneal dialysis catheter was removed. Extensive investigation, including an analysis of heme oxygenase-1 gene promoter region polymorphisms, failed to identify a cause for the renal failure in this patient.
|Title:||Acute renal failure in a patient with paroxysmal cold hemoglobinuria|
|Keywords:||acute renal failure, heme oxygenase-1, paroxysmal cold hemoglobinuria, HEME OXYGENASE-1 GENE, MICROSATELLITE POLYMORPHISM, INTERSTITIAL NEPHRITIS, SUSCEPTIBILITY, HEMOLYSIS, PROMOTER|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science|
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