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Diffuse Lewy body disease presenting with supranuclear gaze palsy, parkinsonism, and dementia: a case report.

de Bruin, VM; Lees, AJ; Daniel, SE; (1992) Diffuse Lewy body disease presenting with supranuclear gaze palsy, parkinsonism, and dementia: a case report. Mov Disord , 7 (4) pp. 355-358. 10.1002/mds.870070410.

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Abstract

A 67-year-old man with a family history of parkinsonism had visual complaints due to difficulty in convergence, which was followed 2 years later by development of bradykinesia and rigidity. The diagnosis of Steele-Richardson-Olszewski syndrome was made on the basis of a supranuclear gaze palsy, bradykinesia, rigidity, and poor response to levodopa. However, subsequent neuropathological examination revealed diffuse Lewy body disease with no evidence of neurofibrillary tangles involving either subcortical or brain stem structures.

Type: Article
Title: Diffuse Lewy body disease presenting with supranuclear gaze palsy, parkinsonism, and dementia: a case report.
Location: United States
DOI: 10.1002/mds.870070410
Keywords: Aged, Alzheimer Disease, Brain, Dementia, Diagnosis, Differential, Eye Movements, Humans, Lewy Bodies, Male, Neurologic Examination, Parkinson Disease, Parkinson Disease, Secondary, Supranuclear Palsy, Progressive
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences
URI: http://discovery.ucl.ac.uk/id/eprint/116179
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