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Contrast echocardiography versus gated single photon emission computed tomography for the assessment of parameters of left ventricular remodeling after acute myocardial infarction

Lim, TK; Burden, L; Janardhanan, R; Dwivedi, G; Ping, C; Moon, J; ... Senior, R; + view all (2006) Contrast echocardiography versus gated single photon emission computed tomography for the assessment of parameters of left ventricular remodeling after acute myocardial infarction. J AM SOC ECHOCARDIOG , 19 (3) 280 - 284. 10.1016/j.echo.2005.10.010.

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Abstract

Background: Assessment of parameters of left ventricular (LV) remodeling after acute myocardial infarction (AMI) has both therapeutic and prognostic implication. Contrast echocardiography (CE) has the advantage of simultaneously assessing myocardial perfusion and LV remodeling. We aimed to evaluate the accuracy of CE to assess LV remodeling after AMI compared with technetium-99m sestamibi gated single photon emission computed tomography (SPECT).Methods: Accordingly, 36 consecutive patients underwent gated SPECT, CE, and cardiovascular magnetic resonance imaging (CMR) 7 to 10 days after AMI. LV ejection fraction (LVEF), and LV end-systolic and end-diastolic volumes were assessed.Results: Absolute differences for LVEF and LV end-diastolic volume between CMR and CE were significantly smaller than that between CMR and SPECT. CE estimate of LVEF more accurately classified patients into LVEF less than 35%, 35% to 45%, and greater than 45% (agreement = 83%, kappa = 0.66 with CMR) compared with SPECT (agreement 61%, kappa = 0.36 with CMR).Conclusion: CE is more accurate than gated SPECT for the estimation of LV remodeling after AMI.

Type:Article
Title:Contrast echocardiography versus gated single photon emission computed tomography for the assessment of parameters of left ventricular remodeling after acute myocardial infarction
DOI:10.1016/j.echo.2005.10.010
Keywords:CARDIOVASCULAR MAGNETIC-RESONANCE, EJECTION FRACTION, PERFUSION SPECT, VOLUMES, ACCURACY, SURVIVAL, CARVEDILOL, MOTION, RISK, MRI
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science

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