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The threshold for diagnosing impaired fasting glucose: a position statement by the European Diabetes Epidemiology Group

Forouhi, NG; Balkau, B; Borch-Johnsen, K; Dekker, J; Glumer, C; Qiao, Q; Spijkerman, A; ... EDEG, ; + view all (2006) The threshold for diagnosing impaired fasting glucose: a position statement by the European Diabetes Epidemiology Group. DIABETOLOGIA , 49 (5) 822 - 827. 10.1007/s00125-006-0189-4.

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Abstract

The category of IFG was introduced in the late 1990s to denote a state of non-diabetic hyperglycaemia defined by a fasting plasma glucose (FPG) concentration between 6.1 and 6.9 mmol/l. In 2003 the American Diabetes Association recommended that this diagnostic threshold be lowered to 5.6 mmol/l. The justification for lowering the threshold has been questioned. This simple change in cut-off value creates a pandemic of IFG, with a two- to five-fold increase in the prevalence of IFG across the world. Such a change in threshold has far-reaching public health implications. The European Diabetes Epidemiology Group (EDEG) has reviewed the evidence for this lower cut-off point for the definition of IFG and concludes that the previous definition should not be altered. EDEG further recommends that the value of all categorical definitions of non-diabetic hyperglycaemia should be reconsidered.

Type: Article
Title: The threshold for diagnosing impaired fasting glucose: a position statement by the European Diabetes Epidemiology Group
DOI: 10.1007/s00125-006-0189-4
Keywords: RANDOMIZED CONTROLLED-TRIAL, DISEASE RISK-FACTORS, CARDIOVASCULAR-DISEASE, PLASMA-GLUCOSE, LIFE-STYLE, HEART-DISEASE, FOLLOW-UP, TOLERANCE, HYPERGLYCEMIA, MORTALITY
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: http://discovery.ucl.ac.uk/id/eprint/113080
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