Brull, DJ and Sanders, J and Rumley, A and Lowe, GDO and Humphries, SE and Montgomery, HE (2001) Statin therapy and the acute inflammatory response after coronary artery bypass grafting. AM J CARDIOL , 88 (4) 431 - +.
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Abstract
Preoperative statin therapy has been shown to improve cardiovascular outcome after coronary artery bypass grafting; however, the clinical gain achieved is in excess of the reduction in lipids. We demonstrate that statin therapy exerts a direct anti-inflammatory effect mediated through reduced interleukin-6 production.
| Type: | Article |
|---|---|
| Title: | Statin therapy and the acute inflammatory response after coronary artery bypass grafting |
| Keywords: | HEART-DISEASE, PRAVASTATIN, SURVIVAL, ATHEROSCLEROSIS, INTERLEUKIN-6, SIMVASTATIN, PROGRESSION, REDUCTION, WALL, MEN |
| UCL classification: | UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of) > Clinical Physiology UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science |
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