UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Brain metabolites as 1H NMR markers of neuronal and glial disorders.

Gill, SS; Small, RK; Thomas, DG; Patel, P; Porteous, R; Van Bruggen, N; Gadian, DG; ... Williams, SR; + view all (1989) Brain metabolites as 1H NMR markers of neuronal and glial disorders. NMR Biomed , 2 (5-6) pp. 196-200.

Full text not available from this repository.

Abstract

1H NMR spectroscopy of human brain in vivo can be used to detect a number of cerebral metabolites including N-acetylaspartate, creatine + phosphocreatine and choline-containing compounds. We have used 1H NMR spectroscopy to analyse these signals in (i) biopsy material from both normal human brain and astrocytomas, and (ii) primary astrocyte cultures. On the basis of this analysis, we conclude that in vivo 1H NMR spectroscopy could play an important clinical role in the non-invasive assessment of neuronal degeneration and proliferation of non-neuronal cells.

Type: Article
Title: Brain metabolites as 1H NMR markers of neuronal and glial disorders.
Location: England
Keywords: Animals, Astrocytes, Brain Neoplasms, Glioblastoma, Humans, In Vitro Techniques, Magnetic Resonance Spectroscopy, Rats, Rats, Inbred Strains
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health
URI: http://discovery.ucl.ac.uk/id/eprint/112247
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item