Thompson, CS and Mikhailidis, DP and Gill, DS and Jeremy, JY and Bell, JL and Dandona, P (1989) Effect of starvation and sampling time on plasma alkaline phosphatase activity and calcium homeostasis in the rat. Lab Anim , 23 (1) 53 - 58.
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Abstract
The effect of starvation and sampling time on plasma alkaline phosphatase activity, total plasma calcium concentration and whole blood ionized calcium concentration was determined in the rat. Starvation caused a significant fall in total and ionized calcium concentrations as well as in alkaline phosphatase activity. These changes were accompanied by a fall in whole blood pH and an increase in the anion gap and a decrease in urinary excretion of calcium. These indices were restored to normal following refeeding. There was no change in serum 25-OH vitamin D concentrations following starvation for 3 days. Alkaline phosphatase activity showed a pattern compatible with the presence of a circadian rhythm when sampling took place between 0800 and 1800 h. Total and ionized calcium concentrations did not show such a rhythm when animals were fed the present diet
| Type: | Article |
|---|---|
| Title: | Effect of starvation and sampling time on plasma alkaline phosphatase activity and calcium homeostasis in the rat |
| Additional information: | DA - 19890707IS - 0023-6772 (Print)LA - engPT - Journal ArticleRN - 0 (Ergocalciferols)RN - 21343-40-8 (25-Hydroxyvitamin D 2)RN - 7440-70-2 (Calcium)RN - EC 3.1.3.1 (Alkaline Phosphatase)SB - IM |
| Keywords: | 25-Hydroxyvitamin D 2, Alkaline Phosphatase, analogs &, Animals, blood, Body Weight, Calcium, Circadian Rhythm, derivatives, Ergocalciferols, Homeostasis, Male, metabolism, pathology, Rats, Rats, Inbred Strains, Starvation, Time Factors, urine, veterinary |
| UCL classification: | UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Surgery and Interventional Science (Division of) > Research Department of General Surgery |
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