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The effect of WNT5B IVS3C>G on the susceptibility to type 2 diabetes in UK Caucasian subjects.

Salpea, KD; Gable, DR; Cooper, JA; Stephens, JW; Hurel, SJ; Ireland, HA; ... Humphries, SE; + view all (2009) The effect of WNT5B IVS3C>G on the susceptibility to type 2 diabetes in UK Caucasian subjects. Nutr Metab Cardiovasc Dis , 19 (2) 140 - 145. 10.1016/j.numecd.2008.02.009.

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Abstract

The wnt signaling pathway regulates adipogenesis and insulin secretion. The WNT5B gene has been reported to confer susceptibility to type 2 diabetes (T2D) in the Japanese population, and we therefore evaluated this in Caucasian subjects with respect to obesity status.

Type:Article
Title:The effect of WNT5B IVS3C>G on the susceptibility to type 2 diabetes in UK Caucasian subjects.
Location:Germany
DOI:10.1016/j.numecd.2008.02.009
Language:English
Keywords:Body Mass Index, Case-Control Studies, Diabetes Mellitus, Type 2, European Continental Ancestry Group, Female, Gene Frequency, Genetic Predisposition to Disease, Great Britain, Humans, Male, Middle Aged, Obesity, Odds Ratio, Polymorphism, Single Nucleotide, Prospective Studies, Risk Assessment, Risk Factors, TCF Transcription Factors, Time Factors, Transcription Factor 7-Like 2 Protein, Wnt Proteins
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science

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