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MHCDB - DATABASE OF THE HUMAN MHC

NEWELL, WR; TROWSDALE, J; BECK, S; (1994) MHCDB - DATABASE OF THE HUMAN MHC. IMMUNOGENETICS , 40 (2) 109 - 115.

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Abstract

Genetic and physical data relating to the human major histocompatibility complex (MHC) were compiled and analyzed, using a genome analysis program. The current contents of the database include: 1) location of over 100 genes and other markers; 2) location of over 250 YAC and cosmid clones; 3) 150 kilobases of genomic DNA sequence including full annotation (exon/intron boundaries, repeats, promoters, etc.); 4) cDNA sequences of currently-known class I and class II alleles; and 5) accompanying descriptive data - references, comments, laboratory addresses, and so on. The database allows rapid access, retrieval, and display of all these data, which should make it a useful tool for the study of the human MHC. MHCDB is publicly available and will be updated as new data become available.

Type:Article
Title:MHCDB - DATABASE OF THE HUMAN MHC
Keywords:MAJOR HISTOCOMPATIBILITY COMPLEX, CLASS-II REGION, YEAST ARTIFICIAL CHROMOSOMES, NUCLEOTIDE-SEQUENCES, GENE ORGANIZATION, HLA-B, CLUSTER, DNA, SUBREGIONS, CONTAINS
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Wolfson Institute and Cancer Institute Administration > Cancer Institute > Research Department of Cancer Biology
UCL > School of BEAMS > Faculty of Maths and Physical Sciences > Physics and Astronomy

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