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Outlet strut fracture of Björk-Shiley convexo concave heart valves: the UK cohort study.

Omar, RZ; Morton, LS; Halliday, DA; Danns, EM; Beirne, MT; Blot, WJ; Taylor, KM; (2001) Outlet strut fracture of Björk-Shiley convexo concave heart valves: the UK cohort study. Heart , 86 (1) pp. 57-62.

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OBJECTIVE: To investigate the risk of outlet strut fracture (OSF) in Björk-Shiley convexo concave (BSCC) valves in relation to patients' clinical and valve characteristics. DESIGN: A cohort of 2977 patients with 3325 valves with a follow up of 18 years. SETTING: 38 cardiac implantation centres in the UK. RESULTS: 56 OSF events were reported with 43 occurring in mitral and 13 in aortic valves. The overall OSF rate was 0.17%/year. No dominant clinical factor of risk was found, but multiple regression analysis identified age, body surface area, valve size, shop order fracture rate, and manufacturing period as risk factors for OSF. A 4% (95% confidence interval (CI) 2% to 6%) decrease in the risk of OSF was observed for each advancing year of age and a fivefold (95% CI 2 to 13) increase in risk for a 0.5 m(2) increase in body surface area. The association between the risk of OSF and valve size was not constant over time. Excess risks among 31 mm and 33 mm sizes (mainly mitral valves) decreased over time while that for 23 mm (almost all aortic valves) increased. The risk of OSF increased by 40% (95% CI 20% to 50%) for a unit increase in the fracture rate of other valves in the same batch. For valves manufactured during 1981 to 1984 the risk of OSF was 4 (95% CI 2 to 12) times greater than for valves manufactured before 1981. CONCLUSIONS: The OSF rates for 60 degrees BSCC valves observed in the UK are the highest among all monitored populations. The changing patterns of mitral and aortic valve OSF rates over time observed in this study have not been identified previously and highlight the need for continued monitoring of patients with the BSCC valve.

Type: Article
Title: Outlet strut fracture of Björk-Shiley convexo concave heart valves: the UK cohort study.
Location: England
Keywords: Adult, Analysis of Variance, Aortic Valve, Cohort Studies, Female, Follow-Up Studies, Heart Valve Prosthesis, Heart Valve Prosthesis Implantation, Humans, Male, Middle Aged, Mitral Valve, Proportional Hazards Models, Prosthesis Failure, Risk, United Kingdom
UCL classification: UCL > Office of the President and Provost
UCL > School of BEAMS
URI: http://discovery.ucl.ac.uk/id/eprint/105413
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