UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

An elastically compressible phantom material with mechanical and x-ray attenuation properties equivalent to breast tissue

Price, BD; Gibson, AP; Tan, LT; Royle, GJ; (2010) An elastically compressible phantom material with mechanical and x-ray attenuation properties equivalent to breast tissue. PHYS MED BIOL , 55 (4) 1177 - 1188. 10.1088/0031-9155/55/4/018.

Full text not available from this repository.

Abstract

We have developed a novel phantom material: a solution of polyvinyl alcohol (PVAL) in ethanol and water, freeze-thawed to produce a solid yet elastically compressible gel. The x-ray attenuation and mechanical properties of these gels are compared with published measurements of breast tissue. Gels with PVAL concentrations from 5 to 20% w/v were produced. The linear x-ray attenuation coefficients of these gels range from 0.76 to 0.86 cm(-1) at 17.5 keV, increasing with PVAL concentration. These values are very similar to the published values of breast tissue at this energy, 0.8-0.9 cm(-1). Under compression cancerous breast tissue is approximately ten times stiffer than healthy breast tissue. The Young's moduli of the gels increase with PVAL concentration. Varying the PVAL concentration from 7.5 to 20% w/v produces gels with Young's moduli from 20 to 220 kPa at 15% strain. These values are characteristic of normal and cancerous breast tissue, respectively.

Type:Article
Title:An elastically compressible phantom material with mechanical and x-ray attenuation properties equivalent to breast tissue
DOI:10.1088/0031-9155/55/4/018
Keywords:MAGNETIC-RESONANCE-ELASTOGRAPHY, MR ELASTOGRAPHY, BIOLOGICAL TISSUES, REGISTRATION, HYDROGEL, DENSITY, MODULI, MODEL
UCL classification:UCL > School of BEAMS > Faculty of Engineering Science > Civil, Environmental and Geomatic Engineering
UCL > School of BEAMS > Faculty of Engineering Science > Medical Physics and Bioengineering

Archive Staff Only: edit this record