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Acute, sub-acute and long-term subjective consequences of 'ecstasy' (MDMA) consumption in 430 regular users

Verheyden, SL; Henry, JA; Curran, HV; (2003) Acute, sub-acute and long-term subjective consequences of 'ecstasy' (MDMA) consumption in 430 regular users. HUM PSYCHOPHARM CLIN , 18 (7) 507 - 517. 10.1002/hup.529.

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Abstract

This study examined the reported psychological effects of different patterns of MDMA use in men and women, and how they are modified by use of other psychoactive substances. A semi-structured inter-view was conducted with 466 regular MDMA users, exploring the perceived acute, sub-acute and long-term subjective effects of this drug. Factor analysis established three main categories of acute effects of MDMA: (i) positive and (ii) negative effects on mental health, and (iii) physical effects. In terms of subacute effects, 83% of participants reported experiencing low mood and 80% reported impaired concentration between ecstasy-taking sessions. Factors affecting these effects included age, gender, extent of MDMA use and concomitant use of cocaine or amphetamine. The long-term effects most frequently reported included the development of tolerance to MDMA (59%), impaired ability to concentrate (38%), depression (37%) and 'feeling more open towards people' (31%). In terms of what might persuade users to stop using MDMA, their most prominent concern was the drug's long-term effects on mental health. Copyright (C) 2003 John Wiley Sons, Ltd.

Type: Article
Title: Acute, sub-acute and long-term subjective consequences of 'ecstasy' (MDMA) consumption in 430 regular users
DOI: 10.1002/hup.529
Keywords: ecstasy, MDMA, survey, depression, BRAIN-SEROTONIN NEURONS, 3,4-METHYLENEDIOXYMETHAMPHETAMINE MDMA, COGNITIVE PERFORMANCE, GENDER DIFFERENCES, NEUROTOXICITY, MOOD, DRUG, +/-3,4-METHYLENEDIOXYMETHAMPHETAMINE, COCAINE, HUMANS
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
URI: http://discovery.ucl.ac.uk/id/eprint/105075
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