UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Angry cognitive bias, trait aggression and impulsivity in substance users

Bond, AJ; Verheyden, SL; Wingrove, J; Curran, HV; (2004) Angry cognitive bias, trait aggression and impulsivity in substance users. PSYCHOPHARMACOLOGY , 171 (3) 331 - 339. 10.1007/s00213-003-1585-9.

Full text not available from this repository.

Abstract

Rationale. According to cognitive theory, people who are aggressive expect angry responses to ambiguous situations. Increased aggression has been reported a few days or weeks following use of MDMA (ecstasy). This may relate to low 5-HT release, and so a 5-HT challenge may increase cognitive bias towards anger differentially in MDMA users and non-users. Objectives. To investigate whether: (1) measures of anger and aggression will correlate with processing time of angry material and with generation of aggressive responses and (2) tryptophan challenge in people abstinent from MDMA and controls will affect angry cognitive bias. Methods. Thirty-two current MDMA users abstinent for 3 weeks, 32 ex-users abstinent for longer than 1 year and 32 non-MDMA substance users were recruited. Trait measures were administered before and state measures before and 5 h after an amino acid drink, depleted or augmented with tryptophan. After the drink, subjects undertook a computer task, which involved reading ambiguous short stories. Reading times to a key sentence describing an angry or non-angry reaction were recorded and subjects wrote a continuing sentence for half the stories. Results. Subjects were faster to process angry than non-angry reactions, indicating the presence of angry cognitive bias. Trait anger and aggression were correlated with processing time of angry relative to non-angry reactions, particularly in the current users. Impulsivity was correlated with non-specific speed of response. Subjects wrote more aggressive sentences after an angry reaction. Tryptophan depletion tended to increase aggressive content. Trait aggression was correlated with aggressive content following non-angry reactions. Conclusions. Evidence of angry cognitive bias was shown in this group of substance users, which was not specific to MDMA use. People high on trait aggression were more likely to expect an angry reaction to an ambiguous situation and to generate more written aggression when this did not occur.

Type: Article
Title: Angry cognitive bias, trait aggression and impulsivity in substance users
DOI: 10.1007/s00213-003-1585-9
Keywords: MDMA, abstinent, aggression, anger, impulsivity, cognitive bias, ECSTASY MDMA, (+/-)3,4-METHYLENE-DIOXYMETHAMPHETAMINE ECSTASY, SEROTONERGIC FUNCTION, TRYPTOPHAN DEPLETION, USE HISTORY, MOOD, BEHAVIOR, HUMANS, DEPENDENCE, ANGER
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Clinical, Edu and Hlth Psychology
URI: http://discovery.ucl.ac.uk/id/eprint/105042
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item